In large-scale apple juice industries, 25% of the raw material becomes waste, mainly represented by the apple pomace. An eco-friendly solution to this situation is the apple pomace valorization in a biorefinery concept. Once this waste contains many nutritional compounds, such as antioxidants, fermentable sugars, and dietary fibers, its chemical characteristics present potential for biomaterials and bioenergy recovery by anaerobic digestion, extraction, and fermentation to obtain value-added products. This study aimed to identify the most promising technological routes for the valorization of apple pomace in the literature, suggesting implementing a biorefinery to support a circular bioeconomy and mitigate environmental side-effects. The final results identify several technological routes to byproducts conversion: pectin, antioxidants, phenolic compounds, bioethanol, methane, xylitol, acid acetic, dietary fibers, emulsifiers, xyloglucan, bio-based films, and 3D objects. Also, it conclused that the benefits of implementing a biorefinery and promoting a circular bioeconomy model include improvements in the social, economic, and environmental spheres, demonstrating its importance and necessity for industries and society.