Maneb is a fungicide widely used in agriculture practice, but its ingestion can provoke Parkinson’s disease, teratogenicity, skin irritation, and sensitization. Hence, it is necessary the determination of the maneb in foods. The purpose was the development of a methodology using the Liquid-Phase Microextraction (LPME) of the maneb in foodstuffs with posterior determination by Flow injection analysis-Flame Absorption Atomic Spectroscopy (FIA-FAAS). Analytical signal manganese and maneb were very similar, permitting maneb determination indirectly using FIA-FAAS (279.9 nm). Extraction optimization of the physical experimental parameters was made employing fractional factorial designs, which were sample mass (x1), extractor solution volume (x2), centrifugation speed (x3) and time (x4), and agitation time (x5). The proposed model was expressed by equation (Recovery=46.92–11.07x2+7.69x4–9.59x22+7,74x42). The solvent extractor used was a solution of 1.0 mmol L-1 of the EDTA at pH 9.5, which had a recovery of 108.0% in the tomato sample. Agitation was an orbital shaker because did not degrade the standard and it had a good recovery. Optimum conditions were 200 mg of the sample, which was doped with 8.80 µmol/L of maneb, extractor volume of 685 µL, centrifuge speed of 4000 rpm and time of 10 min, and agitation time of 10 min, that had recovery in the tomato, apple, and papaya of 91.24±7.91%, 94.50±5.65%, and 85.36±4.08% that demonstrated the extraction efficiency. Curve analytical had linear range from 0.9101 to 20.00 µmol/L maneb (Abs=6.1x10-4C(µmol/L)+1.1x10-4), good repeatability (RSD, 4.0%), detection (0.2 µmol/L) and quantification (0.7 µmol/L) limit. Nebulization and matrix effects were evaluated by slopes of curves in samples verifying that did not have interferences. Furthermore, the effect of concomitant species tests demonstrated that only phosphates can provide interfere in the analyses. Thus, with the methodology proposed was possible the extraction of maneb in foodstuff, showing that the method is simple, quick, and robust.