THE EVOLUTION AND PROFILE OF MULTIRESISTANT TUBERCULOSIS CASES OF AP 5.1, NOTIFIED BETWEEN 2010 AND 2015

INTRODUCTION AND OBJECTIVE Improper use of drugs for the treatment of tuberculosis cases is related to the emergence of multidrug-resistant strains that represent a significant threat to disease control. This study objectives to describe the evolution and profile of MDR-TB cases reported between 2010 and 2015. METHODOLOGY A sectional study of cases of multidrug-resistant tuberculosis, residents of PA 5.1, notified between 2010 and 2015. What were used as a source were a GAL, SITETB and SINAN NET. For the analysis, the SPSS® software version 21 was used. RESULTS AND CONCLUSION There was an increase of cases in the period, increasing from 8 cases in 2010 to 19 in 2014 and 23 in 2015. Multidrug resistance remained as the most prevalent pattern of resistance, contributing to almost 80% of cases per year. Regarding the type of entry, about 70.0% were new cases of MDR-TB. For the 23 cases reported in 2015, 82.6% were covered by the ESF and 43.5% of UBS had MDR-TB cases in their area. It was observed that 86.9% of them were monitoring the area where they lived. In 2015, 43.5% of patients were 30-49 years old, with an education background between 4-7 years (47.8%); 52.2% were mixed and male. The most frequently resistant drugs were R (39.1%) and RHESOfx (21.7%). For abandonment, 13.0% returned after default and 4.35% had the abandonment and closure. It was seen that 43.5% had at least one comorbidity; 26.09% of the population were smokers and drinkers, and 13.0% were drug users.