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The evaluation in the spatial distribution of the congenital syphilis cases supports the decision taking with potential to impact the epidemiological profile of congenital syphilis in the area. The objective was analyze the spatial distribution of congenital syphilis cases, in Health Programme Area 51 residents, in the municipality of Rio de Janeiro. A sectional study carried out on 173 of congenital syphilis cases, diagnosed in 2014, in mothers that reside in PA 5.1, in the municipality of Rio de Janeiro. It was used the municipal basic data from SINAN, updated in March 2015. The reference unit group that was evaluated was composed of 14 units of Health Family Strategy/HFS (Type A) and 07 units formed with traditional model team and HFS (Type B). It was geoprocessed 173 notifications of congenital syphilis. It was seen that 68,79% of the notified cases are located in areas that are covered by the HFS. The units that stand out were: the unit 15 with a frequency of 15,03% from the total of notified and domiciled cases in the area, with a cover of 20,00% by the HFS. The unit 14 with 12,72% of the diagnosed cases in the area, with a cover of 20,00% by the HFS and the unit 10 with 8,67% and 39,80% of covered area by the HFS. It can be noticed that the three units highlighted, all type B, contributed with almost 40% of the cases, with a percentage of cover well below the average presented in the area.