EOSINOPHILIC ESOPHAGITIS: A REVIEW

Introduction and Objective Eosinophilic esophagitis is a condition characterized by gastrointestinal symptoms, especially esophageal associated with hyperplasia of the squamous epithelium. The pathogenesis is not well elucidated, most patients present hypersensitivity evidence to certain foods and airborne allergens. The annual incidence is 12.8 cases per 100,000 inhabitants. Performing a literature review about the signs and symptoms, diagnosis and treatment of eosinophilic esophagitis Methods This article consists of a literature review using journal articles indexed in the SCIELO Discussion and results Symptoms vary according to age, manifesting itself by poor feeding, irritability, vomiting, symptoms of gastro-oesophageal reflux, aversion to food and also underweight and crescimento.A disease is diagnosed by upper endoscopy Digestive ( EDA) with biopsy, showing presence of 15 eosinophils / high power field in one or more fragments. It is necessary absence of gastroesophageal reflux disease, which is ruled by pH monitoring of the distal esophagus or therapeutic failure of proton pump inhibitors. The abnormalities found in EDA are longitudinal grooves, friability, edema, plaques or whitish exudates, esophagus and traqueização mucosa.Não narrowing there are reports that the disease can malignizar over time. In addition, there is no reduction in life expectancy in people diagnosed. Dietary therapy and oral corticosteroids are the initial therapeutic options. Systemic corticosteroids are reserved for critically ill patients. Eosinophilic esophagitis should be considered in patients who do not respond to treatment of the disease of the esophageal reflux. The analysis of the number of eosinophils should be considered to make the diagnosis.