ENVIRONMENTAL RISK BY THE USE OF ANTIBIOTICS AND THEIR EXCRETION IN THE COMPREHENSIVENESS AREA OF A PUBLIC PRIMARY CARE PRACTICE.

Introduction and objective: Emerging contaminants, among which particularly include the antibiotics, are an important surface and effluents water pollutants, for having biological characteristics of persistence and bioaccumulation that unchain alterations in the aquatic and soil life cycle. The aim of this research was to contribute for the recognition and sizing of this problem. Method: An analysis of the environmental risks generated by antibiotics prescribed in a public primary care practice in Curitiba, state of Paraná, was conducted from 2006 to 2010, excreted volume and the calculation of the Predict Environmental Concentration (PEC), on the respective comprehensiveness area. Results and conclusions: Out of the twelve identified antibiotics , four presented exclusively high risk: amoxicillin, ampicillin, benzylpenicillin and erythromycin . Sulfamethoxazole presented high risk in only one year and itpresented medium risk in the others four years. Metronidazole, trimethoprim and azithromycin presented medium risk. Cephalosporins (cephalexin, cephuroxime and ceftriaxone ) presented low risk. For β- lactam (amoxicillin, ampicillin, benzylpenicillin ) , erythromycin ) , sulfamethoxazole , metronidazole, trimethoprim and azithromycin administered, medium and high environmental risk was found.Among physicians the disclosure and awareness of the deposit of these pollutants in soil and groundwater may make the prescription of antibiotics more diligent and responsible , influencing these professionals when choosing these drugs, promoting a responsible prescription involving the health of people and the environment integrating them.