The growing consumption of vegetables by the population represents a breakthrough for good nutrition, but lack of adequate sanitation can pose risks to the health of those who consume them. The Brazilian cerrado contains plant species with potential for use as natural sanitizers. In this study the antimicrobial ability of hydro-alcoholic extracts of taruma were evaluated for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella spp., Listeria monocytogenes and Candida albicans. The disk diffusion test of the pulp extract revealed an inhibition zone of 12,0mm for S. aureus and did not differ significantly (p <0.05) when compared to inhibition zones of antibiotics; vancomycin, gentamicin, and azithromycin. The inhibition zone of the bark extract (7.0mm) for E. coli and of the seed (9,2mm) for P. aeruginosa were not significantly different (p <0.05) from the inhibition zone of tetracycline. The seed extract showed an inhibition zone of 10.0mm for L. monocytogenes and 7 mm for Salmonella sp., of which were not significantly different (p <0.05) from the inhibition zones of gentamicin, and tetracycline. The hydro-alcoholic extracts of the bark, pulp and seed of tarumã, except for C. albicans showed minimal inhibitory concentration for all the microorganisms of this study.