Several species of anurans place eggs into or nearby temporary ponds maintained by rainfall. Such bodies of water may suffer great variations in environmental factors and tadpoles growing within such ponds need to cope with these variations. Due to small amounts of water present in temporary ponds and high water temperatures, the amount of dissolved oxygen may become significantly reduced, decreasing the oxygen available for aquatic gas exchange. Thus, we tested the effect of aquatic hypoxia on the development of tadpoles from Leptodactylus labyrinthicus, Physalaemus nattereri and Physalaemus sp. (CEUA-FFCLRP n°17.5.119.59.3). Freshly laid egg clutches were collected nearby Igarapava-Rifaina (SISBIO n°56564-1-8), and maintained in the laboratory for 50 days at 26±2°C. Clutches were either maintained under aquatic normoxia (120-140mmHg) or aquatic hypoxia (40-80mmHg), maintained by bubbling normoxic air or N2, respectively, into the tadpoles recipient. All tadpoles received fish feed and had their dechlorinated water exchanged every 2-3 days. At 2, 5, 10, 20, 30, 40, and 50 days of maintenance, some animals were removed to weigh them. P. nattereri tadpoles maintained under hypoxia did show a significantly greater body mass throughout development when compared to tadpoles maintained under normoxia and resulted in more metamorphosed individuals in hypoxia after 50 days. L. labyrinthicus and Physalaemus sp. tadpoles did not show significant differences in body mass and the number of metamorphosed individuals after 50 days was also similar. Clearly, P. nattereri tadpoles showed accelerated growth under hypoxia, in contrast to the other two species tested. If this differential growth is related to different pulmonary gas exchange capacities, is currently under investigation.