Paepalanthus belongs to Eriocaulaceae family and it is one of the most diverse genera in Brazil, with an endemism rate equivalent to 95.7%.1 It has distribution throughout territory, but the greatest center of diversity occurs in the “Cadeia do Espinhaço”.2 Despite this, few species of the genus have been chemically studied. Thus, the aim of this study is to carry out a literature review on isolated compounds in the Paepalanthus genus. Papers were accessed from six platforms such as SciFinder® and ScienceDirect. Forty papers were evaluated, within isolated and/or identified compounds. The research evidenced eighty-seven compounds from the flavonoids (64.4%) and naphthopyranones (35.6%) classes. Among the compounds of the flavonoids class were isolated derivatives of apigenin, luteolin, kaempferol, patuletin and quercetin. So far, 30 naphthopyranones and 1 naphthoquinone have been isolated from Paepalanthus species.