Sabine Gilch

University of Calgary

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Papers 7

Uncovering neurotoxic and neuroprotective mechanisms driven by PrPC-ligand interactions
Mirza, Aiman Riaz ¹
Zemlyankina, Irina ¹
Gilch, Sabine ¹
¹ University of Calgary
Vol 1, 2025 -
329784

Pathogenic mechanisms in prion and prion-like diseases

Abstract Prion 2025
Characterizing subclinical infection and strain evolution in gene-targeted mouse models of CWD (Authors: Kristen Gregg, Maria Arifin, Anja Itum, Raychal Ng, Samia Hannaoui, Sabine Gilch)
Gregg, Kristen ¹
Arifin, Maria ¹
Itum, Anja ¹
Ng, Raychal ¹
HANNAOUI, SAMIA ²
Gilch, Sabine ¹
¹ Faculty of Veterinary Medicine, University of Calgary
² University of Calgary
Vol 1, 2025 -
329780

Animal prion diseases

Abstract Prion 2025
Can altering cholesterol homeostasis alleviate prion disease? Authors: Jessica Cashion, Tahir Ali, Anja Itum, Samia Hannaoui, Sabine Gilch
Cashion, Jessica ¹
Gilch, Sabine ¹
¹ University of Calgary
Vol 1, 2025 -
329691

Therapeutic approaches for prion and prion-like diseases

Abstract Prion 2025
Neuronal cholesterol upregulation affects prion propagation through altering PrPC metabolism
Yilmaz, Gokhan ¹
Randhawa, Rajpreet ¹
Cherry, Pearl ²
Wilson, Nicole ²
Shim, Su Yeon ²
Gilch, Sabine ²
¹ University of Calgary
² Calgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Vol 1, 2025 -
329659

Pathogenic mechanisms in prion and prion-like diseases

Abstract Prion 2025
Treatment with anti-retroviral drug Efavirenz activates cholesterol hydroxylation and extends survival in Creutzfeldt-Jakob disease model
Gilch, Sabine ¹
Ali, Tahir ²
Cashion, Jessica ¹
HANNAOUI, SAMIA ¹
Ahmed-Hassan, Hanaa ³
Schätzl, Hermann ⁴
¹ University of Calgary
² Ottawa University
³ Calgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
⁴ Calgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Calgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Vol 1, 2025 -
328790

Therapeutic approaches for prion and prion-like diseases

Abstract Prion 2025

PRION 2025

Proceedings of the Prion 2025 - Advancing the understanding and treatment of prion diseases

Sabine Gilch

Uncovering neurotoxic and neuroprotective mechanisms driven by PrPC-ligand interactions

Characterizing subclinical infection and strain evolution in gene-targeted mouse models of CWD (Authors: Kristen Gregg, Maria Arifin, Anja Itum, Raychal Ng, Samia Hannaoui, Sabine Gilch)

Can altering cholesterol homeostasis alleviate prion disease? Authors: Jessica Cashion, Tahir Ali, Anja Itum, Samia Hannaoui, Sabine Gilch

Neuronal cholesterol upregulation affects prion propagation through altering PrPC metabolism

Treatment with anti-retroviral drug Efavirenz activates cholesterol hydroxylation and extends survival in Creutzfeldt-Jakob disease model

Co-authors (25)

SAMIA HANNAOUI

Irina Zemlyankina

Jessica Cashion

Hanaa Ahmed-Hassan

Hermann Schätzl

Maria Arifin

Aiman Riaz Mirza

Kristen Gregg

Maria Arifin

Anja Itum

Raychal Ng

Gokhan Yilmaz

Rajpreet Randhawa

Pearl Cherry

Nicole Wilson

Su Yeon Shim

Tahir Ali

Mary Lavoie

Christopher Chang

Dalia Abdelaziz

Yo-Ching Cheng

Kevin Low

Shirely Phan

Byron Kruger

Chimone Stefni Dalton

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