JESUS REQUENA | PRION 2025 | Galoá Proceedings

University of Santiago de Compostela

JESUS REQUENA

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Preclinical Development of Folding Interfering Degraders Against the Cellular Prion Protein
Innocenti, Nicole ¹
Zeni, Ilaria ²
Gasparotto, Dino ³
Massignan, Tania ⁴
Copat, Laura ⁴
Parolin, Eleonora ³
Susin, Giorgia ¹
Perrucci, Cecilia ¹
Brugnara, Samuele ¹
Casagranda, Massimo ¹
Ambrosino, Giacomo ¹
Bellini, Martina ¹
Trubnikova, Tatiana ¹
Spagnolli, Giovanni ⁴
Astolfi, Andrea ⁵
Ragni, Maria Grazia ⁵
Faccioli, Pietro ⁶
Santambrogio, Carlo ⁷
Grandori, Rita ⁷
REQUENA, JESUS ⁸
Tähtinen, Petri ⁹
Mancini, Ines ¹⁰
Barreca, Maria Letizia ⁵
Biasini, Emiliano ³
¹ Department of Cellular, Computational and Integrative Biology (CIBIO), and Department of Physics, University of Trento (ITALY)
² University of Trento
³ Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento (ITALY)
⁴ Sibylla Biotech, OpenZone Campus, Bresso (ITALY)
⁵ Department of Pharmaceutical Sciences, University of Perugia (ITALY)
⁶ Department of Physics, and Department of Biotechnology and Biosciences, University of Milan Bicocca (ITALY)
⁷ Department of Biotechnology and Biosciences, University of Milan Bicocca (ITALY)
⁸ University of Santiago de Compostela
⁹ Department of Chemistry, University of Turku (Finland)
¹⁰ Department of Physics, University of Trento (ITALY)
Vol 1, 2025 -
329493

Therapeutic approaches for prion and prion-like diseases

Abstract Prion 2025
Structural Dynamics and Kinetic Interplay in Prion Assembly
Vazquez, Raul Cacheiro ¹
Rezaei, Human ²
REQUENA, JESUS ³
Béringue, Vincent ²
Igel, Angelique ²
¹ CIMUS
² Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
³ University of Santiago de Compostela
Vol 1, 2025 -
328684

Pathogenic mechanisms in prion and prion-like diseases

Abstract Prion 2025
“Procrustean bed”: Preliminary modelling of the very first steps of PrPC conversion to PrPSc through Molecular Dynamics
REQUENA, JESUS ¹
Arias, Iria Díaz ²
Biasini, Emiliano ³
Rigoli, Marta ⁴
¹ University of Santiago de Compostela
² Universidade de Santiago
³ Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento (ITALY)
⁴ University of Trento
Vol 1, 2025 -
328642

Protein structure, function, conversion, and dysfunction

Abstract Prion 2025

Co-authors (29)