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Benchtop NMR spectrometers have seen great advancements in magnet performance and capabilities to be implemented in a wide scope of applications. The high performance and compact size of benchtop NMR spectrometers shift the practice of NMR analysis to bringing the spectrometers to the samples, instead of the traditional approach of bringing the samples to the dedicated high-field NMR facilities. This approach enables the placement of benchtop NMR spectrometers next to the reactors, or in the process environment to provide real-time NMR data of samples in non-deuterated solvents. This presentation will discuss recent advances in the solvent suppression techniques on benchtop NMR spectrometers that enable the 1D and 2D analyses of analytes and complex mixtures in protonated solvents. Overall, the compact size and versatility of benchtop NMR spectrometers enables the integration of powerful NMR techniques into processes that weren’t accessible by NMR before.
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