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Question
Effects of red laser
Publication: Evaluation of the effects of low-power lasers on gene expression of stem phenotype markers and breast cancer spheroids viability
Hello, Luiza, good afternoon! Congratulations on the great presentation and incredible work! I have a question: I would like to know if the investigation of the effects of these radiations is aimed at cancer treatment or if it is to develop safer protocols for cancer patients to use for the therapeutic purposes mentioned in the video? I would also like to know if you plan to investigate other cellular events, besides cell proliferation. Thank you! -
Question
Methodology
Publication: Effects of Photobiomodulation by Infrared Radiation on Cancer Hallmarks in Cellular Regulatory Pathways - Review
Hello, Ana Caroline, good evening! Congratulations on your presentation! I would like to know if, depending on the physical irradiation parameters used, these results could be different? Also, do you plan to study which possible pathways are related to the processes mentioned in the results? -
Other
PBM and Proliferation Gene Regulation in MCF-7 Cells
Publication: Evaluation of the Effects of Photobiomodulation with Low-Power Red Laser and Ultraviolet A LED on Cell Survival and Antioxidant Markers in MCF-7 Breast Cancer Cells
Great presentation Ana Clara! Considering that PBM with red laser and UVA-LED did not modulate survival or antioxidant genes but increased MKI67 expression, how do you interpret the specificity of PBM in regulating proliferation-related genes in MCF-7 cells? -
Other
Gene choice
Publication: Evaluation of the Effects of Photobiomodulation with Low-Power Red Laser and Ultraviolet A LED on Cell Survival and Antioxidant Markers in MCF-7 Breast Cancer Cells
Good evening, Ana Clara. Congratulations on your work; the quality of life of cancer patients is extremely important. Ana, do you plan to evaluate other genes? If so, which ones do you consider essential for studying photobiomodulation in tumor cells? -
Question
Methodology
Publication: Combined brachydins, A, B, and C, induced cytotoxicity by the activation of the intrinsic mitochondrial apoptosis pathway
Hello, Celina, good evening! Congratulations on your presentation and the excellent work! I would like to know, in order to verify this selective effect on cancer cells, do you intend to observe the effects of brachydins on non-tumoral breast cells, such as MCF-10A? Do you plan to observe these effects in another breast cancer cell line? And do you intend to analyze the protein levels of the genes analyzed by RT-qPCR? Thank you!
Publications in other proceedings
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XVIII SO 2024
DUAL INHIBITION OF REDOX APE1 AND STAT3 DECREASES CELL AGGRESSIVENESS OF LUMINAL A BREAST CANCER CELLS
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XVIII SO 2024
TNF-alpha PATHWAY EXHIBITED HIGHER mRNA LEVELS IN THE BREAST CANCER BASAL SUBTYPE AND TNF INHIBITOR REDUCES CELL VIABILITY
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XVIII SO 2024
THE EFFECTS OF LOW-POWER RED LASER AND ULTRAVIOLET A LED ON CELL VIABILITY, PROLIFERATION, AND CELL SURVIVAL GENES EXPRESSION IN MCF-7 BREAST CANCER CELLS
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