VITAMIN D AND ITS CLINICAL OUTCOMES : AN EPIDEMIOLOGICAL STUDY

Objectives:Identify the vitamin D levels in patients followed at a specialized Cystic Fibrosis(CF);Associate vitamin D values with presence of pancreatic insufficiency and nutritional status. METHODS: Retrospective, descriptive, quantitative study of medical charts from 21 pediatric patients with CF accompanied in ambulatory specialist Fortaleza–CE.The study was place between September and December 2015 by filling a standardized form. The sérum 25-hydroxyvitamin D(25-OHD) was measured with chemiluminescence enzyme imunoassay. Vitamin D deficiency was defined as below 20ng/ml; insufficiency of 20-30ng/ml and sufficiency 30-50ng/ml. For evaluation of pancreatic insufficiency use the positivity SUDAM III with higher reference values than 5% of fecal fat. Results:The 25-OHD status was measured in 21 patients;47.6%(10) showed vitamin D insufficiency and 23.8%(5) deficiency of vitamin D totaling a percentage of 71.4%(15) of hypovitaminosis. Among them, it was identified growth rate reduced and low weight gain in 73.3%(11);53.3%(8) were pancreatic insufficiency with changes in analysis of SUDAM III and diarrhea;80%(12) using a support dose of fat soluble vitamins. We identified 33.3%(5) of the sample with Body Mass Index