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Introduction: The epidemic of HIV infection and SIDA constitutes a serious problem of public and global health. Health campaigns worldwide attempt to reduce the prevalence and incidence rates being necessary to study the impact of these measures on the number of occurrence of this disease. Objective: To identify the cases of SIDA in Brazil over a period of 15 years (between 2000 and 2014). Method: It is a quantitative ecological study with cross-sectional design. We consider the total SIDA cases occurred in Brazil recognized by the National Health System. The data used were obtained from the Ambulatory Information System. At the same time a study was conducted in the IBGE (Brazilian Institute of Geography and Statistics) for the number of survey of the population. Results: The average prevalence of SIDA in Brazil between the years 2000 to 2015 was 0.18%. The highest peak prevalence corresponded to year 2002 (0.22%) and the lowest prevalence rate was in 2014 (0.07%) showing a significant reduction in the rates at response to government actions of prevention in health care. Male gender presented a rates more than female rate with corresponding prevalence Conclusion: The study showed a significant reduction in the number of cases of AIDS in Brazil between 2013 and 2014. It should be investigated whether this reduction is due to the increased mortality or decline in incidence rates.of 0.25% with a lower value and rate equivalent to 0.10% and 0.39% respectively.