ARTERIAL HYPERTENSION CONTROL (AHC) IN AN QUASI EXPERIMENTAL STUDY OF SIVASTATIN/EZETIMIBE

Introduction: The AHC is the risk factor with the world's greatest death percentage (13.5% of the total), asymptomatic, with adherence to treatment. Method: Analysis of data of the arterial pressure of a quasi experimental study(before and after with crossover) for intervention with simvastatin+ezetimibe, follow-up of 14 months, with 50 patients; all diabetic, hypertensive, hypercholesterolemic and with family history of cardiovascular disease. Test signed-ranks Wilcoxon test for paired variables. Stat9. Results: The women represented 58% of the studied sample(29people), the average age of the population was 63.8 years-old, with 29 women of 65year-old and the 21 men of 62 years. 56% used an ACEI, 50% a calcium channel blocker, 72% made use of two or more antihypertensive drugs. Before the study 13 patients(26%) had pressure below 140/90mmHg. At the end of the monitoring, the pressure of all patients was below 140/90, being that 17 had it below 130/80mmHg (decrease occurred in all patients, higher in those who had higher pressure). The drop in systolic pressure(SBP) was 23,4mmHg and the diastolic blood pressure(DBP) was of 26.5% in relation to the baseline situation and the end of the monitoring. Conclusion: High risk patients for cardiovascular disease and with low adherence to treatment. With minor modifications of their medication and orientation of life habits, there was a significant drop in SBP and DBP, which shows that the main intervention concerned the study itself, with a better doctor-patient relationship, the establishment of a common project therapeutic and, with this, improvement of adherence to the therapy