Technological materials emitting infrared may exert positive physiological effects on skeletal muscle. Studies have shown that far-infrared (FIR) can increase availability of nitric oxide and calcium in cell culture, and delay fatigue during ex-vivo skeletal muscle contractions. However, FIR effects on muscle performance in humans are poorly studied. Here, using a double-blind, placebo-controlled, crossover design, we show that individuals in FIR condition had a higher maximun knee extensors torque before and after fatigue protocol and obtained higher values of total work in dynamic exercise. These findings demonstrate the ergogenic effect of FIR on neuromuscular performance in humans.