Retrospective study evaluating the incidence of skin cancer in renal transplant patients. Of a total of 2,400 transplanted patients, 85 fulfilled the inclusion criteria of the study, with 352 tumors diagnosed, about 108 months post transplantation. More than half of the patients analyzed had more than one tumor (multiple or recurrent), but there was no difference between the characteristics of patients with single or multiple tumors. In both groups, most tumors affected the head and neck, but in the group with multiple tumors, we observed an increase in lesions in limbs over time. Unlike the general population, where basal cell carcinoma is the most frequent form, among the transplanted patients the most common tumor was squamous cell carcinoma, with different degrees of differentiation.