Orange bagasse is a low cost agroindustrial residue that possesses high carbohydrate levels, high susceptibility to enzymatic hydrolysis, and it does not compete with food production; such characteristics make bagasse a promising source of carbon for the production of second-generation ethanol. The cellulases are enzymes able to hydolyse cellulosic substrates, such as biomass, producing monosaccharides for posterior fermentation. We propose the immobilization of a recombinant cellulase from Xanthomonas axonopodis pv. citri in the surface of magnetic nanoparticles aiming the enzyme reuse and process cost reduction.