We studied, by PCR Real Time technics, the participation of plasticity-related genes (bdnf and karln) in the context of seizures in zebrafish larvae brain at 2 different times after induction of seizures. Some of the results differ from what is described in the adult model, so we can consider the effects of neuroplasticity of the developing brain in the response to a seizure; still, consider other times studied would bring a better characterization of the expression of analysed genes.