Segmented polyurethanes (SPUs) based on PEG, PTMC and PLLA as macrodiols, HDI as diisocyanate and BDO as chain extender were synthetized and characterized with respect to composition, thermal and dynamical mechanical properties. The SPUs are heterogeneous and the thermal events observed in DSC and DMA analyses are related to the macrodiols components, being affected by the global composition.