Microbial Fuel Cells (MFC) are bioelectrochemical systems that combine wastewater treatment and energy generation, meeting the increasing demand for sustainable development technologies. In these systems, the electrode materials are determinant for obtaining high power densities. This study tested different anode modifications in dual-chamber MFCs fed with whey. The materials that presented better performance were those that combined higher surface area, greater conductivity and better maintenance of pH above 5.0.