Also published on: SBQT 2023
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Publication: Carbon nanohorn as nanocontainer for cisplatin: insights on the interaction with plasma membranes of normal and breast cancer ce
Hello Eduardo, using QM/MM? this was not clear to me. Some assumptions how body will get rid of the nanocarrier (if necessary?). Some consideration on the mechanism how will be cisplatin released to cell? It is not clear to me what is C-memb and N-memb?
Thanks
Jaroslav
Best regards to Helio.
nanocontainer for cisplatin
Publication: Carbon nanohorn as nanocontainer for cisplatin: insights on the interaction with plasma membranes of normal and breast cancer ce
Belo trabalho, Eduardo!
Duas perguntas breves: a cisplatina é possivelmente o radio-sensibilizador mais utilzado, e creio que seja primordialmente utilizado sem encapsulamento
1) Qual(is) seria(m) as vantagens terapêuticas do encapsulamento
2) O encapslamento interfere na reatividade/ação radio-sensibilizadora da droga? Afeta, digamos, sua capacidade de formar complexos com DNA e/ou outras biomoléculas? Afeta sua eletroafinidade?
Obrigado
Marcio
Parabéns!
Publication: Carbon nanohorn as nanocontainer for cisplatin: insights on the interaction with plasma membranes of normal and breast cancer ce
Parabéns pelo excelente trabalho.
SBBf-2025
EVALUATING MARTINI 2 AND MARTINI 3 FORCE FIELDS FOR LIPOPOLYSACCHARIDES AGGREGATES
SBQT 2023
Modeling the cellular uptake of functionalized carbon nanohorns loaded with cisplatin through a breast cancer cell membrane
43ª RASBQ
Modeling the inclusion complexes of cisplatin and its aquated species with functionalized carbon nanohorns: a quantum chemical approach
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