INFRARED RADIATION LOOK AT BIOLOGICAL SAMPLES AT IMBUIA BEAMLINE ON SIRIUS

IMBUIA Beamline (Infrared Multiscale Beamline for Ultra-resolved Imaging Applications) is an advanced facility dedicated to the study of materials at molecular and nanoscale levels. With its high brightness and integrating spatial and spectral information, the composition and distribution of materials in biological, geological and materials science research is revealed. The versatility of the IMBUIA Beamline, with its synchrotron-based infrared microspectroscopy and imaging capabilities, offers powerful opportunities to delve into the molecular world and gain a deeper understanding of material properties. The use of infrared radiation (IR) in the investigation of biological systems has proven to be a valuable tool to analyze the molecular composition, structure, and dynamics of samples without the need for chemical markers. For example, it can detect DNA damage in fungi exposed to volatile organic compounds, using the natural molecular vibrations of the samples. Infrared imaging has proven particularly useful in cellular research as it facilitates the characterization of local chemical variations and the identification of specific components within complex systems Therefore, the application of IR in the study of biological systems offers benefits such as characterization of biomolecules, spatial imaging, probing interactions and changes and dynamic analysis without relying on chemical markers. These applications will significantly advance our understanding of the biological world and drive technological progress in infrared spectroscopy.