The one-pot Biginelli reaction/nitroaromatic reduction applied to the synthesis of quinazoline-dihydropyrimidinone hybrid

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  • Presentation type: Exposição de Pôster
  • Track: Química Orgânica - ORG
  • Keywords: Biginelli reaction; One-pot; Nitroaromatic reduction; dihydropyrimidinones; Molecular Hybridization;
  • 1 Universidade Federal do Rio Grande do Sul/ IQ (Instituto de Química)
  • 2 Universidade Federal do Rio Grande do Sul

The one-pot Biginelli reaction/nitroaromatic reduction applied to the synthesis of quinazoline-dihydropyrimidinone hybrid

Eduardo Bustos Mass

Universidade Federal do Rio Grande do Sul/ IQ (Instituto de Química)

Abstract

-Novel one-pot Biginelli reaction/nitroaromatic reduction in higher yields than conventional two steps reaction;
-H NMR-pure compounds easily crystallized from ethanol;
-New quinazoline-DHPM hybrid.

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