Test mixture in LC-HRMS untargeted metabolomics: development and application for urine samples

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Details
  • Presentation type: Exposição de Pôster
  • Track: Química Biológica - BIO
  • Keywords: LC-MS; Untargeted metabolomics; urine; Inborn Erros of Metabolism; Test mixture;
  • 1 Instituto de Química, Universidade Federal do Rio de Janeiro

Test mixture in LC-HRMS untargeted metabolomics: development and application for urine samples

Rafael Garrett da Costa

Instituto de Química, Universidade Federal do Rio de Janeiro

Abstract

Visual inspection of pooled QC samples clustering in PCA space do not guarantee reliable LC-MS data.
Test mixtures must be used together with pooled QCs in untargeted LC-MS metabolomics.

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