The agriculture has the challenge to establish strategies to achieve sustainable production of food. Fertilizers are used to increase crop production by replacing the necessary nutrient and also are the major cause of contamination of underground water and rivers. The big question is how to increase fertilizer efficiency and crop yield without compromising natural resources? One of the answers is developing a material that enhance the fertilizer efficiency, reducing the loss, the amount of fertilizer applied and, consequently, production costs. For this purpose, the aim of this work was to develop microspheres of starch and micronutrients (Fe²⁺, Cu²⁺ and Mn²⁺) by spray drying technique. First, we carried out the gelatinization of starch (conditions: oil bath with magnetic stirring, 97 ºC, 30 min). After, monoelementary dispersions of starch/micronutrients were done by adding the micronutrients separately and homogenized in a Turrax for 5 min with 10,000 rpm and during the atomization process kept in magnetic stirring. For starch/micronutrient atomization, we use a 2 - fluid nozzle (0.5 mm diameter) at 130 ºC and aspiration rate of 10 % in a Mini spray dryer (B290/Buchi), Figure 1 (A). The yield was 44.51, 39.54 and 47.85 % for Starch-Cu, Starch-Fe, and Starch-Mn, respectively. For the release teste, microspheres of starch/micro (0.5 g) were conditioned in a semi-permeable sachet of TNT and immersed in 50 mL of distilled water. At pre-established times, the sachet containing the material was removed and immersed in a new recipient containing the same volume of distilled water. The released micronutrients were quantified by Atomic Absorption Spectrometry. During the 8 days of the test, the release profile was similar for the microspheres containing different micronutrients. The microspheres release 60 % of the nutrients in 60 min, following the increasing order Fe²⁺<Mn²⁺<Cu²⁺, 56, 58 and 64% released, respectively. In 8 days, the increasing order of release became Mn²⁺<Fe²⁺<Cu²⁺, 74, 85 and 86%, respectively, Figure 1 (B). FTIR analyses corroborate the micronutrient release profile, where the Fe²⁺ and Mn²⁺ micronutrients have stronger interaction (more intense the shift of the OH bond to higher wavelength), slower release, and Cu²⁺, weaker interaction (less intense the shift of the OH bond to higher wavelength), faster release in water. It was possible to establish that the release profile of micronutrients in water is related to the interaction force between the inorganic salt cation and the ‒OH groups of starch. The interaction was more intense for Fe²⁺ and Mn²⁺ cations, prolonging the release and less intense for Cu²⁺, promoting a faster release in water.