Gold nanoparticles (AuNPs) are considered materials of great interest due to their singular properties that are strongly dependent of their size and shape. However, the environment around of these particles also produces effects that tune or change completely the properties of the nanostructured systems, e.g. solvents, surfactants, particle concentration, etc. In this sense, this work aims to develop methodologies to attain nanostructured materials via tailor-made self-assembling processes, using AuNPs with different morphologies as building blocks. The spherical AuNPs (AuNSs) were synthesized by the Turkevich method (13 nm in diameter) and the rod-like AuNPs (AuNRs) were obtained by seed mediated method, according to the protocol developed by the El-Sayed group (45 x 15 nm), and their colloids showed characteristic UV-vis absorption spectra. To induce a specific process of self-assembly of AuNSs and AuNRs, we modified the surface of each AuNPs type with specific molecules with suitable functional groups - Cysteamine (CYS) contain amine and tiol groups and Mercaptoacetic acid (AMA) contain carboxylic acid and tiol group. After surface modification, the two sets of AuNP colloids were mixed, i.e. AuNS/CYS and AuNR/AMA together with EDC and NHS to allow C-N bond formation. We noted that after mixing, the Uv-vis absorption spectra of the mixture radically changed. This was not just a superposition of the two previous spectra before mixing. This characteristic suggest that particle interactions are in process. Nevertheless, until now, under dry conditions, the expected self-assembled arrange was not observed (on TEM grids). Further studies on sample preparation are in progress.