New Thiopyrimidinones from Base-catalyzed Thiol-Ene Coupling as Aldose Reductase Inhibitors

Download
Favorite this paper
How to cite this paper?
Details
  • Presentation type: Exposição de Pôster
  • Track: Química Orgânica - ORG
  • Keywords: 2-Thiopyrimidinones; TEC coupling; Aldose reductase inhibition;

Authors:

  • 1 UNIVERSIDADE FEDERAL DE PERNAMBUCO
  • 2 UNIVERSIDADE DE PERNAMBUCO

New Thiopyrimidinones from Base-catalyzed Thiol-Ene Coupling as Aldose Reductase Inhibitors

Sidney Gustavo Diniz Feitosa

Universidade Federal de Pernambuco

Abstract

Unprecedented modification of 2-thiopyrimidinones via thiol-ene coupling;
We synthesized 35 2-thiopyrimidinones derivatives;
Some derivatives showed good aldose reductase inhibition.

Share your ideas or questions with the authors!

Did you know that the greatest stimulus in scientific and cultural development is curiosity? Leave your questions or suggestions to the author!

Sign in to interact

Have a question or suggestion? Share your feedback with the authors!