Copper(II) complexes and their aroylhydrazone ligands as potential anticancer drugs

Download
Favorite this paper
How to cite this paper?
Details
  • Presentation type: Exposição de Pôster
  • Track: Química Medicinal - MED
  • Keywords: copper complexes; aroylhydrazone ligands; anticancer agents; metal chelation;

Authors:

  • 1 Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio)
  • 2 Institut Parisien de Chimie Moléculaire (IPCM), Sorbonne Université

Copper(II) complexes and their aroylhydrazone ligands as potential anticancer drugs

Jesica Paola Rada Arias

Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio)

Abstract

Novel Cu2(II)-complexes and aroylhydrazonic ligands.
DNA interaction studies.
Metallation and transmetallation of biological ions.
Pyridine-compounds versus phenol-compounds anticancer properties.

Questions (2 topics)

Share your ideas or questions with the authors!

Did you know that the greatest stimulus in scientific and cultural development is curiosity? Leave your questions or suggestions to the author!

Sign in to interact

Have a question or suggestion? Share your feedback with the authors!

Author

Jesica Paola Rada Arias

Olá Jocely, obrigada !

-A linhagem não cancerigena foi a Madin-Darby Canine Kidney (MDCK) line cell. Os valores experimentais podem ser observados na ultima linha da Tabela 1.  

-Para o cálculo do SI, usamos a razão entre o valor de IC50 do controle (MDCK cells) e os valores das linhagens cancerigenas.

Fico ao dispor.

Jocely de Lucena Dutra

Obrigada Jesica! 

Author

Jesica Paola Rada Arias

Obrigada Gustavo.