QuEChERS-SPE method for determination of endocrine disrupting compounds in harbor sediment

Endocrine disrupting compounds (EDCs) including synthetic and natural hormones, commonly found in aquatic systems mainly as result of wastewater treatment discharges where they can reach all compartments due to the broad range of physicochemical properties. focousing EDCs occurrence in natural water more abundant than on sediments (river or sea), however for ecotoxicological studies are very important the EDcs determination in both environmental compartments to eva marine biota exposition. The analytical is to determine EDCs at very low concentration high complexicity matrices, as sediments. In this work we present a method coupling QuEChERS and SPE for hormones (17 estradiol -E2, 17α ethinylestradiol -EE2 -E3) determination in harbor sediment Quantification was carried out by fluorescence detector. On figure 1 we show all extraction process. Recovery on spiked samples (five concentrations ranged 20 CV<16%, LOD for E3, E2 and EE2 was for all studied hormones. For harbor high concentration E3 in all samples close to LOQ.