45S5 Bioglass Scaffold to repair bone tissue damages

The 45S5 Bioglass® is one the most promising materials to be used in bone tissue damages, especially due to its biocompatibility, bioactivity and osteoinduction. However, the production of BG 45S5 scaffolds with a good compromise between porosity and mechanical properties results in the crystallization of the glass because of its small sintering window, lowering the properties that make it such an interesting material. In this work, 45S5 scaffolds were produced using particles of this glass made by melt and quenching together with the “Fritas” method, binding them using a 45S5 Bioglass® film produced by sol-gel, and surfactant and hydrogen peroxide to produce pores. The characterization of the final material was made with microscopy and XRD. A non-crystalline white scaffold (Figure 1) with pores between 50 and 100 m was obtained. The sol-gel did not cover the particles homogeneously as it was indicated by the SEM image (Figure 2) where some rough regions are observed.