Introduction: Alcohol use is a global phenomenon, it is estimated that 24.7% of people in the world use this substance and that each individual consumes 6.2 liters of pure alcohol per year approximately, which is equivalent to 13.4 grams of pure alcohol per day (1). Also, many people have risk or harmful use of alcohol, which can bring a lot of health problems if you do not have an appropriate intervention. As the main strategy to counter the increase in the number of individuals with harmful use of alcohol, WHO recommends some measures that have shown be effective in different care places, among them is the brief intervention (2) although it was efficient and effective in some European countries and the United States, has shown some difficulties in its implementation in the Latin context, due to configuration health systems, lack of human resources and structure among others (3). Aim: The aim of this review is to systematically review the evidence to determine the best available evidence related to the effectiveness of brief interventions in group to reduce of pattern drink in adults with harmful and hazardous alcohol use when compared with the usual care or other therapies. Method: It is a Systematic review which the papers selected for retrieval had been assessed for methodological validity using standardized critical appraisal instruments from the Joanna Briggs Institute, Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI). The review considered both experimental and epidemiological study designs including randomized controlled trials, non-randomized controlled trials, quasi-experimental studies, before and after studies, prospective and retrospective cohort studies, case control studies and analytical cross sectional studies for inclusion. Results: Ninety-two studies were found and three studies met the eligibility criteria. Providing brief intervention in group format have the same effectiveness as the individual brief intervention. However this studies presented some methodological failures. Conclusions: The included papers are inconclusive, but with a positive tendency in the reduction of the use pattern of the population with harmful alcohol use when compared with other therapies.