Yerba mate (Ilex paraguariensis) is a plant in South America, mainly in Brazil, Argentina, Paraguay, Uruguay, and Chile. It has bioactive compounds, such as saponins, methylxanthines, and phenolic compounds. The present study aimed to evaluate the yerba mate extract obtained by percolation, microencapsulated in maltodextrin, and dried by spray drying. For this, Scanning Electron Microscopy - SEM, Fourier Transform Infrared Spectroscopy - FTIR, X-ray Diffraction - XRD, Particle Size, Ultra-High Performance Liquid Chromatography coupled to Mass Spectrometry - UHPLC -MS/MS, Solubility, Encapsulation Efficiency, pH, a_w and instrumental colorimetry were performed. SEM indicated particles with rough surfaces and a spherical shape, as well as the presence of apparent fissures and cracks. FTIR analysis showed a large vibration between the frequencies of 3000 and 3500 cm^-1, indicating the presence of aromatic stretching, alkyne stretching, hydroxyl group, OH stretching, dimeric OH stretching, terminal vinyl, and vinylidene. In contrast, other frequencies indicated the presence of methyl, methylene stretching, methine stretching, methyl and methylamino ether, aromatic ring stretching, and esters. XRD analysis revealed that the yerba mate extract presented a high degree of amorphization between the 2θ = 15 and 20º peak, revealing components of the extract in a crystalline state. The particle size presented a bimodal distribution, with peaks ranging from 10 to 40000 nm. UHPLC-MS/MS analysis revealed the presence of chlorogenic, gallic, vanillic, caffeic, coumaric, ferulic acids, and 4-hydroxybenzoic acid, in addition to kaempferol and quercetin. The microencapsulation efficiency was 12.8%, which influenced the values ​​of solubility, pH, a_w, instrumental colorimetry, and stability evaluated for 30 days.