ROLE OF ADENOSINE IN HYDRO-ELECTROLYTE BALANCE

Hyperosmolarity of body fluid induces specialized cells in the hypothalamus to trigger the sensation of thirst and motivate the drinking behavior. Nevertheless, the complete signaling pathways and the identity of most of the cells that receive the information to regulate the hydromineral balance, remain unknown. Recent studies have shown that hyperosmolarity releases adenosine to the extracellular medium, and we hypothesized that this purine may be involved in osmotic responses