REPEATED DOSES OF IVERMECTIN INDUCED LOCOMOTOR CHANGES AND DEPRESSIVE-LIKE EFFECT IN RATS.

Introduction: In 2020, World Health Organization declared the beginning of the COVID-19 pandemic, which is caused by the Sars-cov-2 virus, which initially causes a respiratory syndrome, and in some cases can worsen the patient`s condition, leading to hospitalization, resulting in increasing cases of death and overcrowding of hospitals worldwide. Due to the general picture of this the disease and its potential risk, several drugs have been used as possible treatments and prevention for COVID-19. At this point, ivermectin, which is a drug used to treat various parasitic infestations, was implemented without scientific evidence of its effectiveness.