PERIPHERAL BLOOD CELL PROFILE IN AN IN VIVO MODEL OF T-CELL LYMPHOBLASTIC LEUKEMIA/LYMPHOMA

T-cell lymphoblastic leukemia/lymphoma (T-LLL) is a neoplasia originating from a single hematopoietic precursor committed to the T-cell lineage. Given that in vitro data indicate the involvement of different membrane receptors, sphingolipids, and other molecules in the migration of T-LLL blasts, our group aimed to establish an in vivo model to study the differences between the leukemic and the lymphomatous forms of T-LLL in terms of cell migration and preferential localization. In this regard, the analysis of the cellular profile in peripheral blood seeks to aid in the establishment of the developing in vivo model.