Maternal High-Fat Diet promotes delay in parameters of the neurodevelopment while the neonatal supplementation with 5-HTP and Pyridoxine reduces reflex delay.

Maternal high-fat diet (HFD) promotes deleterious effects on the offspring’s neurological development while supplementation of 5-HTP, the immediate percussor of serotonin, acts during the critical period as important neurotrophic factor potentiated when associated with vitamin B6.