Fucosylated chondroitin sulfate derived from Holothuria grisea as treatment for experimental airway inflammation

Asthma is a disease characterized by reversible airflow obstruction, which is generated by increased mucus production, recruitment of immune system cells, bronchoconstriction and collagen deposition around the airways. Fucosylated chondroitin sulfate (FucCS) extracted from sea cucumber Holothuria grisea is a glycosaminoglycan with anticoagulant, anti-inflammatory and antitumor properties, like heparin.