EXPLORING SEIZURE DYNAMICS IN FOCAL TEMPORAL LOBE EPILEPSY USING VECTOR-EEG

Although Epilepsy is commonly viewed as a syndrome, given its multiple causes and manifestations, a surprisingly consistent abnormally activated circuit is recruited during the ictogenesis process of any given patient. Therefore, the dynamics of seizures in terms of spatiotemporal propagation is paramount for diagnosis, seizure prediction and treatment. Despite advances in neural dynamics recording techniques, the temporal resolution of deep brain electrical activity is indisputable, in spite of its lacking spatial resolution. In fact, the spatial origin of neuronal activity is bound, among other aspects, by the number of electrodes, the electrode size and the cerebral substrate in which the electrodes are implanted. The Vector-EEG technique proposed here aims to enhance spatially derived information and provide a high temporal precision vector as well as magnitude and direction related to the dipoles foci during the neural activity.