Effects of the probiotic Lactobacillus rhamnosus LB1.5 on obesity parameters, metabolic disorders, anxiety-like behavior, innate fear and cognitive function in middle-aged mice fed a high-fat diet

A high-fat diet (HFD) throughout their lifetime contributes to the development of obesity and metabolic disorders and may exacerbate age-related cognitive deficits. Probiotic supplementation may be an alternative to improve health by reducing obesity parameters, mitigating the consequences of HFD, and potentially increasing life expectancy.