EFFECTS OF MODERATE CAFFEINE CONSUMPTION ON BEHAVIOR AND NEUROINFLAMMATORY MARKERS IN ANIMAL MODEL OF RATS SELECTED BY BEHAVIORAL FREEZING

Anxiety is a typically human feeling that helps for a good performance and is characterized by the feeling of fear and tension against danger. However, when this response is exacerbated, it can lead to anxiety disorders that are among the most common mental illnesses. Caffeine, the most consumed psychoactive substance in the world, has a dual impact on anxiety and has been associated with modulation of glial cells activation and neurochemical changes in the hippocampus.