EFFECTS OF A CARBOHYDRATE-RESTRICTED AND HIGH-PROTEIN DIET ASSOCIATED OR NOT TO EXERCISE ON INFLAMMATORY MARKERS IN THE SUBCUTANEOUS ADIPOSE TISSUE IN OBESE RATS

Adipose tissue undergoes important morphological and functional changes that impact health in obese mammalians. Dysfunction in the pattern of secreted cytokines from adipose tissue and local recruitment of immune cells favors a local and systemic pro-inflammatory state. Dietary interventions, as well as physical training are identified as relevant strategies to counteract this pro-inflammatory state. However, there are few studies that evaluate the effects of the concomitant application of a carbohydrate-restricted and high-protein diet associated or not to physical training as an intervention to counteract the effects of obesity.