Anais da XXXVII Reunião Anual da FeSBE

The adherent junction plays several roles, such as initiation and stabilization of cell-cell adhesion, intracellular signaling and transcriptional regulation. One way of regulating and maintaining adherent junctions is through the action of proteins from the TGFb family, which play an important role in placentation, embryogenesis and decidualization. Despite controversial data about its signaling, TGFb plays a fundamental role in the development of the human placenta and in the establishment of the maternal-fetal interface