EFFECT OF EXERCISE TRAINING ON RENAL APOPTOSIS AND MACROPHAGE EXPRESSION IN FEMALE RATS WITH TYPE 1 DIABETES

Diabetic kidney disease (DKD) develops progressively after the onset of hyperglycemia, which can lead to activation of mitogen-activated protein kinases (MAPKs), which are associated with crucial processes in disease pathogenesis, including apoptosis and inflammatory cell influx. For this, new therapeutic strategies are needed to attenuate the progression of the DKD, especially in females.