ACUTE INTRACEREBROVENTRICULAR STIMULUS WITH INTERESTERIFIED LIPID CONTAINING SATURATED FATTY ACID IN THE SN-2 POSITION MODULES ENERGY HOMEOSTASIS IN MICE

Approximately 95% of dietary fat is composed of triacylglycerols (TAGs), in which the fatty acids located in the outer part of the TAG structure are called sn-1 and sn-3, while the fatty acid located in the center is sn-2. Interesterified fat is obtained by processing vegetable oils by chemical or enzymatic methods, which results in the rearrangement of the fatty acids in the glycerol molecule without changing their degree of saturation. Studies on the effect of acute stimulation of interesterified lipids on the central nervous system (CNS), specifically the hypothalamus, the region responsible for central control of food intake and energy expenditure, are unknown.