Synthesis and characterization of a tamoxifen-based ruthenium(II)-nitrosyl complex for therapeutic purposes

Breast cancer is the kind of cancer that most affect women in the widely world, which usely treatment is based on tamoxifen. Searchs show that ruthenium(II)-nitrosyl complexes present anticancer action. The Coordination Chemistry allows this three factors to be combined in a one coordination compound, improving its actions. This study sought the synthesis and have been characterized a ruthenium(II)-nitrosyl complex bearing a tamoxifen ligan for future studies against both cancerous and health breast cells.