Methylene Blue Capture by a Novel iMOF-A(Co): Optimization Through Box–Behnken Design of Experiments

Industrial wastewater contamination by synthetic dyes like Methylene Blue (MB) represents a major environmental challenge. Anionic metal-organic frameworks (iMOFs-A) stand out as innovative cation exchangers, as their negatively charged frameworks enhance electrostatic interactions and the removal of cationic pollutants. This study presents the synthesis of a novel cobalt-based iMOF-A applied for MB adsorption. To maximize efficiency and evaluate material reusability, Box–Behnken design of experiments was used to optimize three key operational parameters, pH, dye concentration and adsorbent mass, obtaining a surface response as result. The objective is to determine the optimal conditions for efficient and economically viable pollutant removal.