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HOW A DRUG CAN MAKE YOUR BRAIN FORGET THE WORDS? A LANGUAGE FUNCTIONAL MRI STUDY WITH TOPIRAMATE IN EPILEPSY AND HEADACHE.

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We performed cognitive tests and language functional MRI (fMRI) study with healthy volunteers, patients with headache and others with epilepsy to demonstrate how TOPIRAMATE hampers words formation. We show poor cognitive performance and alterations on both brain activations and deactivations during the language paradigm fMRI.