Reconhecimento de sulfonamidas por meio de sensor eletroquímico baseado em eletrodo de carbono vítreo modificado com polímero magnético com impressão molecular

In this work we developed a novel sensitive and selective electrochemical sensor, based on modified molecularly imprinted polymer (MIP) glassy carbon electrode (GCE) for sulfanilamide (SN) recognition. The sulfanilamide based magnetic molecularly imprinted polymer (mag-MIP) was first synthesized and then the surface feature of thecore-shellmag-MIPs modified GCE (mag-MIP/GCE) was characterized by cyclic voltammetry (CV). The response behavior of the mag-MIP/GCE electrode, known to affect was studied and optimized by various factors.The developed mag-MIP/GCEsensor showshigh recognition ability and affinity for the template moleculewithgood stability and satisfactoryreproducibility for recognition of SN. Under optimum experimental conditions, satisfactory linearity was observed between thecurrent response of the redox probe, hexacyanoferrate, and SN concentration, rangingfrom 2.5 x 10-5–1.0 x 10-3M, shown the detection limit of 1.53 x 10-6 M. The developed method was effectivelyapplied to analyze SN in milk sampleand with satisfactory recoveries of 94.3–103.5%, representing an excellent characteristic ofthemag-MIP/GCE as asensor towards the recognition of SN in real samples.